Mal-PEG4-VA

Catalog No.: A43285
ADC Linker
Mal-PEG4-VA is a cleavable ADC linker featuring a Maleimide moiety, which enables the selective conjugation of drugs to antibodies. This compound is primarily utilized in the synthesis of antibody-drug conjugates (ADCs), facilitating targeted therapeutic strategies in cancer treatment. Its ability to release the drug in response to specific stimuli enhances the therapeutic efficacy of ADCs while minimizing off-target effects.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-PEG4-VA is a cleavable ADC linker featuring a Maleimide moiety, which enables the selective conjugation of drugs to antibodies. This compound is primarily utilized in the synthesis of antibody-drug conjugates (ADCs), facilitating targeted therapeutic strategies in cancer treatment. Its ability to release the drug in response to specific stimuli enhances the therapeutic efficacy of ADCs while minimizing off-target effects.
Product Information
Catalog NumA43285
FormulaC26H42N4O11
Molecular Weight586.63
CAS Number1800456-31-8
SMILESO=C(C=CC1=O)N1CCC(NCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](C)C(O)=O)=O)=O)=O
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