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Mal-PEG4-VC-PAB-DMEA

Catalog No.: A43169
ADC Linker
Mal-PEG4-VC-PAB-DMEA is a cleavable linker featuring a Maleimide moiety utilized in the design of antibody-drug conjugates (ADCs). This compound facilitates the selective conjugation of cytotoxic agents to antibodies, enhancing targeted delivery to specific cancer cells. Its inherent stability and designed release mechanism make it a valuable tool for researchers developing ADCs in therapeutic and diagnostic applications.
Mal-PEG4-VC-PAB-DMEA 1569261-93-3 ADC Linker
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-PEG4-VC-PAB-DMEA is a cleavable linker featuring a Maleimide moiety utilized in the design of antibody-drug conjugates (ADCs). This compound facilitates the selective conjugation of cytotoxic agents to antibodies, enhancing targeted delivery to specific cancer cells. Its inherent stability and designed release mechanism make it a valuable tool for researchers developing ADCs in therapeutic and diagnostic applications.
Product Information
Catalog NumA43169
FormulaC41H65N9O13
Molecular Weight892.01
CAS Number1569261-93-3
SMILESO=C(C=CC1=O)N1CCC(NCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC(C=C2)=CC=C2COC(N(C)CCNC)=O)=O)=O)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

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Antibody-drug Conjugates (ADC) > ADC Linker