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Mal-PEG8-Val-Ala-PAB-Exatecan

Catalog No.: A41329
Anti-Nectin-4 ADC Linker
Mal-PEG8-Val-Ala-PAB-Exatecan is an anti-Nectin-4 antibody-drug conjugate (ADC) linker designed to facilitate targeted delivery of chemotherapeutic agents. This compound enables precise conjugation to Nectin-4 polypeptides, allowing for enhanced therapeutic efficacy in cancer research applications. Its unique structure promotes stability and release characteristics, making it suitable for studying the effects of ADCs in various tumor models.
Mal-PEG8-Val-Ala-PAB-Exatecan 2679821-39-5 Anti-Nectin-4 ADC Linker
Grouped product items
Size Price Stock Qty
5mg
$450.00
In stock
10mg
$755.00
In stock
25mg
$1,415.00
In stock
50mg
$2,215.00
In stock
100mg
$3,200.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-PEG8-Val-Ala-PAB-Exatecan is an anti-Nectin-4 antibody-drug conjugate (ADC) linker designed to facilitate targeted delivery of chemotherapeutic agents. This compound enables precise conjugation to Nectin-4 polypeptides, allowing for enhanced therapeutic efficacy in cancer research applications. Its unique structure promotes stability and release characteristics, making it suitable for studying the effects of ADCs in various tumor models.
Product Information
Catalog NumA41329
FormulaC66H85FN8O20
Molecular Weight1329.42
CAS Number2679821-39-5
SMILESO=C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)N[C@@H](C(C)C)C(N[C@@H](C)C(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O
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This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > ADC Linker