Fig. 1 · Structure
Documents & Downloads
Malabaricone C
Sphingomyelin Synthase Inhibitor
Malabaricone C is a noncompetitive inhibitor of sphingomyelin synthase (SMS), demonstrating IC50 values of 3 μM for SMS 1 and 1.5 μM for SMS 2. This compound has been shown to reduce body weight gain, enhance glucose tolerance, and decrease hepatic lipid accumulation, effectively preventing high-fat diet-induced fatty liver in murine models. Additionally, Malabaricone C exhibits anti-inflammatory properties, making it a valuable tool for research into obesity and immune disorders linked to T-cell hyperactivation. Its source is the fruit of Myristica cinnamomea King.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 63335-25-1 |
| Applications | Sphingomyelin Synthase Inhibitor |
| Formula | C21H26O5 |
| Molecular Weight | 358.43 |
| SMILES | O=C(C1=C(O)C=CC=C1O)CCCCCCCCC2=CC=C(O)C(O)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.