Fig. 1 · Structure
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Maleimide-C10-NHS ester
PROTAC Linker
Maleimide-C10-NHS ester is a versatile linker designed for use in protein-targeting chimeras (PROTACs) to facilitate targeted protein degradation. This alkyl/ether-based compound allows for efficient conjugation to proteins, enhancing the specificity and efficacy of therapeutic applications. It serves as a vital component in the development of novel PROTACs for research into cellular regulation, protein interactions, and disease mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 87981-04-2 |
| Applications | PROTAC Linker |
| Formula | C19H26N2O6 |
| Molecular Weight | 378.42 |
| SMILES | O=C(ON1C(CCC1=O)=O)CCCCCCCCCCN2C(C=CC2=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.