Fig. 1 · Structure

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Malonganenone A

Antimalarial

Malonganenone A is an antimalarial marine alkaloid that targets the interaction between PfHsp70-x and Hsp40. This compound selectively inhibits the ATPase activity of plasmodial Hsp70 without affecting human Hsp70, interfering with the aggregation suppression activity of PfHsp70-x. Malonganenone A is useful in research focused on malaria therapeutics and the functional modulation of heat shock proteins in Plasmodium species.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 882403-69-2
Applications Antimalarial
Formula C26H38N4O2
Molecular Weight 438.61
SMILES
O=C1N=CN(C)C2=C1N(C/C=C(C)/CC/C=C(C)/CCC/C(C)=C\C(CC(C)C)=O)C=N2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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