Fig. 1 · Structure
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Mammea A/BA
Antitrypanosomal Agent
Mammea A/BA is an effective antitrypanosomal agent targeting Trypanosoma cruzi. It demonstrates significant biological activity by inducing mitochondrial dysfunction, promoting reactive oxygen species (ROS) production, and causing DNA fragmentation. Additionally, Mammea A/BA increases the number of acidic vacuoles and can stimulate apoptosis, autophagy, and necrosis. This compound is valuable for research related to Chagas disease and the exploration of potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 5224-54-4 |
| Applications | Antitrypanosomal Agent |
| Formula | C25H26O5 |
| Molecular Weight | 406.47 |
| SMILES | O=C1C=C(C2=CC=CC=C2)C3=C(O)C(C/C=C(C)\C)=C(O)C(C(CC(C)C)=O)=C3O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.