Fig. 1 · Structure
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Mangafodipir trisodium
Hepatocellular-Specific Contrast Agent
Mangafodipir trisodium is a hepatocellular-specific contrast agent that functions primarily as an antioxidant to mitigate oxidative stress-related damage. It has demonstrated efficacy in inhibiting chemotherapy-induced peripheral neuropathy (CIPN) without compromising the cytotoxic effects of chemotherapy. This makes it a valuable tool in research focusing on liver imaging and the study of oxidative stress in various cellular contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 140678-14-4 |
| Applications | Hepatocellular-Specific Contrast Agent |
| Formula | C22H27MnN4Na3O14P2 |
| Molecular Weight | 757.32 |
| Synonyms | MnDPDP |
| SMILES | O=C1[O-][Mn+2]([N]2(C3)CC4=C5COP(O)(O)=O)([O-]C6=C(N=C7)C)([O-]C4=C(N=C5)C)([O-]C3=O)[N](CC6=C7COP([O-])(O)=O)(CC2)C1.[Na+].[Na+].[Na+] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.