Fig. 1 · Structure
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MARK-IN-4
MARK Inhibitor
MARK-IN-4 is a potent MARK inhibitor with an IC50 of 1 nM. It demonstrates significant biological activity in the regulation of microtubule dynamics, making it a valuable tool in Alzheimer's disease research. This compound allows for the investigation of MARK signaling pathways and their implications in neurodegenerative disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1990492-86-8 |
| Applications | MARK Inhibitor |
| Formula | C21H23N7OS |
| Molecular Weight | 421.52 |
| SMILES | O=C(C1=CC(C2=C3N=CC(C4=CN(C)N=C4)=CN3N=C2)=CS1)N[C@H]5[C@H](N)CCCC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.