Fig. 1 · Structure
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Maropitant citrate hydrate
NK1 Receptor Antagonist
Maropitant citrate hydrate is an orally active antagonist of the neurokinin-1 (NK1) receptor. It exhibits significant antiemetic properties, making it effective in preventing vomiting. Additionally, Maropitant has been reported to inhibit ulcerative dermatitis, highlighting its utility in various research applications related to gastrointestinal and inflammatory conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 359875-09-5 |
| Applications | NK1 Receptor Antagonist |
| Formula | C38H50N2O9 |
| Molecular Weight | 678.81 |
| SMILES | OC(C(O)=O)(CC(O)=O)CC(O)=O.CC(C)(C)C1=CC=C(OC)C(CN[C@@H]2[C@H](C(C3=CC=CC=C3)C4=CC=CC=C4)N5CCC2CC5)=C1.O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.