Fig. 1 · Structure
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MASTL-IN-2
MASTL Inhibitor
MASTL-IN-2 is a selective inhibitor of MASTL (microtubule-associated serine/threonine kinase-like) that demonstrates potent antitumor activity. It inhibits the proliferation of human epithelial MIA PaCa cancer cells with an IC50 of 2.8 nM, making it a valuable tool for cancer research. This compound is relevant for studies focused on cell cycle regulation and cancer therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3024916-69-3 |
| Applications | MASTL Inhibitor |
| Formula | C21H25N7O2 |
| Molecular Weight | 407.47 |
| SMILES | O=C(OCC1)N1C(N=C2N)=CC3=C2C=NC(NC4=NC=CC(C(CC)(N)CC)=C4)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.