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MBL-IN-3

MBL Inhibitor

MBL-IN-3 is an inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1), demonstrating an IC50 value of 54±4 μM. This compound effectively reduces the minimum inhibitory concentrations (MICs) of Meropenem against various clinical isolates of E. coli and K. pneumoniae that express NDM-1. MBL-IN-3 serves as a valuable tool in antibiotic sensitizer research, contributing to the study of antimicrobial resistance mechanisms and potential therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1452395-68-4
Applications	MBL Inhibitor
Formula	C₁₈H₂₁N₃O₅
Molecular Weight	359.38
SMILES	O=C1C(C(N(CC2)CCC32C(O)CCCO3)=O)=CN=C4N1C=CC=C4O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.