Fig. 1 · Structure

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Mc-Asn-Asn-E104

E104+Legumain-cleavable Linker

Mc-Asn-Asn-E104 is a conjugate of E104 and a legumain-cleavable linker, designed to facilitate the synthesis of E104 immunologically selective activity conjugates (ISACs). This reagent enables targeted delivery and controlled release of E104 in biological systems, enhancing its therapeutic efficacy. Research applications include studies in drug development and targeted cancer therapy, where legumain activity can be exploited for selective activation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 3108288-42-9
Applications E104+Legumain-cleavable Linker
Formula C39H46N10O7
Molecular Weight 766.85
SMILES
CCCCC1=NC(C(N)=NC2=CC=CC=C23)=C3N1CC4=CC=C(C=C4)NC([C@H](CC(N)=O)NC([C@H](CC(N)=O)NC(CCCCCN5C(C=CC5=O)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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