Fig. 1 · Structure

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Mc-Gly-Gly-Phe-Gly-PAB-pSar11-Exatecan

Toxin-Linker Compound

Mc-Gly-Gly-Phe-Gly-PAB-pSar11-Exatecan is a toxin-linker compound designed for the development of antibody-drug conjugates (ADCs). This compound facilitates targeted delivery of cytotoxic agents to cancer cells, enhancing the therapeutic efficacy while minimizing off-target effects. Its utility in ADC preparation makes it a valuable tool for researchers investigating novel cancer treatments and drug delivery strategies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2928560-28-3
Applications Toxin-Linker Compound
Formula C91H115FN20O24
Molecular Weight 1892.00
SMILES
CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(C=C(C=C1)NC(CNC([C@@H](NC(CNC(CNC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=C1COC(N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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