Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is a quenched fluorescent peptide substrate specifically designed for matrix metalloproteinases (MMPs). This elongated MMP substrate exhibits enhanced activity against collagenases, including MMP-1, MMP-8, and MMP-13, as well as MT1-MMP, demonstrating higher specificity constants compared to its predecessor, FS-1. It is suitable for real-time quantification of MMP enzymatic activity, making it an essential reagent for studies in tissue remodeling and diseases involving MMP dysregulation. Excitation and emission wavelengths are 325 nm and 400 nm, respectively.
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is a quenched fluorescent peptide substrate specifically designed for matrix metalloproteinases (MMPs). This elongated MMP substrate exhibits enhanced activity against collagenases, including MMP-1, MMP-8, and MMP-13, as well as MT1-MMP, demonstrating higher specificity constants compared to its predecessor, FS-1. It is suitable for real-time quantification of MMP enzymatic activity, making it an essential reagent for studies in tissue remodeling and diseases involving MMP dysregulation. Excitation and emission wavelengths are 325 nm and 400 nm, respectively.
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