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MCC950 sodium

Catalog No.: A13478

NLRP3 inhibitor

MCC950 sodium

MCC950 sodium Chemical Structure

CAS NO. 256373-96-3

MCC950 sodium is a potent NLRP3 inflammasome inhibitor that inhibits IL-1beta production with IC50 value of 7.5 nm.

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Biological Activity

MCC950 sodium is a potent NLRP3 inflammasome inhibitor that inhibits IL-1beta production with IC50 value of 7.5 nm.
In vitro DMSO Insoluble
Water 77 mg/mL (180.55 mM)
Ethanol 36 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.45 mL 117.24 mL 234.49 mL
0.5 mM 4.69 mL 23.45 mL 46.9 mL
1 mM 2.34 mL 11.72 mL 23.45 mL
5 mM 0.47 mL 2.34 mL 4.69 mL

*The above data is based on the productmolecular weight 426.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13478
Actions Inhibitor
CAS No. 256373-96-3
Formula C20H23N2NaO5S
M. Wt 426.46
Purity >98%
Synonyms CP-456773 sodium, CP 456773 sodium, CP456773 sodium, MCC 950, MCC-950, CRID-3, CRID3, CRID 3
SMILES O=S(C1=CC(C(C)(O)C)=CO1)([N-]C(NC2=C3CCCC3=CC4=C2CCC4)=O)=O.[Na+]

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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