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MCG-02

Antiparasitic Agent

MCG-02 is a potent inhibitor of cruzain (CRZ) and cathepsin L-like protease (CATL), demonstrating an IC50 of 0.2 μM and 0.02 μM, respectively. This compound effectively targets Trypanosoma cruzi and Trypanosoma brucei, making it a valuable agent for antiparasitic research. Its mechanism of action provides a basis for exploring therapeutic strategies against Chagas disease and sleeping sickness.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3105537-51-4
Applications	Antiparasitic Agent
Formula	C₁₃H₁₃N₃O₂S
Molecular Weight	275.33
SMILES	CC1=CC=C2C(OC(C(/C(C)=N/NC(N)=S)=C2)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.