Fig. 1 · Structure
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MDL 105212A
NK-1/NK-2 Antagonist
MDL 105212A is a potent, orally active nonpeptide antagonist targeting neurokinin receptors NK-1 and NK-2. This compound exhibits significant potential in studies related to inflammation, immunology, and neurological disorders, including asthma. Its efficacy in modulating tachykinin signaling pathways makes it a valuable tool for researchers investigating these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 167261-60-1 |
| Applications | NK-1/NK-2 Antagonist |
| Formula | C34H40Cl3N3O5 |
| Molecular Weight | 677.06 |
| SMILES | NC(C(CC1)(C2=CC=CC=C2)CCN1CC[C@@]3(C4=CC(Cl)=C(Cl)C=C4)CN(C(C5=CC(OC)=C(OC)C(OC)=C5)=O)CC3)=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.