MDL 105212A

Catalog No.: A62027
NK-1/NK-2 Antagonist
MDL 105212A is a potent, orally active nonpeptide antagonist targeting neurokinin receptors NK-1 and NK-2. This compound exhibits significant potential in studies related to inflammation, immunology, and neurological disorders, including asthma. Its efficacy in modulating tachykinin signaling pathways makes it a valuable tool for researchers investigating these conditions.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMDL 105212A is a potent, orally active nonpeptide antagonist targeting neurokinin receptors NK-1 and NK-2. This compound exhibits significant potential in studies related to inflammation, immunology, and neurological disorders, including asthma. Its efficacy in modulating tachykinin signaling pathways makes it a valuable tool for researchers investigating these conditions.
Product Information
Catalog NumA62027
FormulaC34H40Cl3N3O5
Molecular Weight677.06
CAS Number167261-60-1
SMILESNC(C(CC1)(C2=CC=CC=C2)CCN1CC[C@@]3(C4=CC(Cl)=C(Cl)C=C4)CN(C(C5=CC(OC)=C(OC)C(OC)=C5)=O)CC3)=O.Cl
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