Fig. 1 · Structure

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MDM2-p53-IN-19

Chemical Intermediate

MDM2-p53-IN-19 is a chemical intermediate designed to facilitate the synthesis of inhibitors targeting the MDM2-p53 interaction. This compound plays a critical role in the development of potential anticancer therapeutics by disrupting the MDM2-mediated inhibition of p53, a vital tumor suppressor. It is applicable in research focused on cancer biology and the development of novel cancer treatments.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1818292-01-1
Applications Chemical Intermediate
Formula C23H22Cl2FN3O4
Molecular Weight 494.34
SMILES
OCC[C@H]1[C@@H]([N+]([O-])=O)[C@H](C2=C(C(Cl)=CC=C2)F)[C@@]3(C4=CC=C(Cl)C=C4NC3=O)N1CC5CC5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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