Fig. 1 · Structure

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Me-PEG4-Me

PROTAC Linker

Me-PEG4-Me is a PEG-based linker designed for use in PROTAC (Proteolysis Targeting Chimera) synthesis. This compound facilitates the conjugation of target ligands to E3 ligase ligands, enabling the development of innovative targeted protein degradation strategies. Me-PEG4-Me's hydrophilic nature enhances solubility and biocompatibility, making it suitable for various research applications in the field of protein regulation and degradation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 143-24-8
Applications PROTAC Linker
Formula C10H22O5
Molecular Weight 222.28
Synonyms Tetraglyme
SMILES
COCCOCCOCCOCCOC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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