Me-Tet-PEG3-NH2 is an ADC linker featuring three polyethylene glycol (PEG) units. This compound utilizes its tetrazine moiety to engage in a specific inverse electron demand Diels-Alder (iEDDA) reaction with cyclooctene (TCO) derivatives. It serves as a valuable tool in antibody-drug conjugate (ADC) development, facilitating the site-specific conjugation of cytotoxic agents to antibodies for targeted cancer therapy.
Me-Tet-PEG3-NH2 is an ADC linker featuring three polyethylene glycol (PEG) units. This compound utilizes its tetrazine moiety to engage in a specific inverse electron demand Diels-Alder (iEDDA) reaction with cyclooctene (TCO) derivatives. It serves as a valuable tool in antibody-drug conjugate (ADC) development, facilitating the site-specific conjugation of cytotoxic agents to antibodies for targeted cancer therapy.
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