Me-Tet-PEG4-NHBoc

Catalog No.: A43231
ADC Linker
Me-Tet-PEG4-NHBoc is an ADC linker characterized by the presence of four PEG units and a Tetrazine moiety. It is designed to facilitate a specific inverse electron demand Diels-Alder reaction (iEDDA) with TCO-containing compounds. This functionality enables effective conjugation in antibody-drug conjugate (ADC) applications, enhancing targeted delivery and efficacy in cancer research and other therapeutic areas.
Grouped product items
Size Price Stock Qty
25mg
$1,325.00
In stock
50mg
$1,715.00
In stock
100mg
$2,090.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMe-Tet-PEG4-NHBoc is an ADC linker characterized by the presence of four PEG units and a Tetrazine moiety. It is designed to facilitate a specific inverse electron demand Diels-Alder reaction (iEDDA) with TCO-containing compounds. This functionality enables effective conjugation in antibody-drug conjugate (ADC) applications, enhancing targeted delivery and efficacy in cancer research and other therapeutic areas.
Product Information
Catalog NumA43231
FormulaC26H40N6O7
Molecular Weight548.63
CAS Number2143955-71-7
SMILESO=C(NCCOCCOCCOCCOCCC(NCC1=CC=C(C2=NN=C(C)N=N2)C=C1)=O)OC(C)(C)C
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