Me-Tet-PEG8-Maleimide is an ADC linker featuring eight polyethylene glycol (PEG) units, designed for applications in antibody-drug conjugate (ADC) development. It incorporates a Tetrazine group capable of engaging in a specific inverse electron demand Diels-Alder (iEDDA) reaction with trans-cyclooctene (TCO) compounds, facilitating targeted drug delivery. Additionally, the maleimide functionality exhibits stability in aqueous conditions, making it suitable for various bioconjugation studies and enhancing drug solubility and circulation time.
Me-Tet-PEG8-Maleimide is an ADC linker featuring eight polyethylene glycol (PEG) units, designed for applications in antibody-drug conjugate (ADC) development. It incorporates a Tetrazine group capable of engaging in a specific inverse electron demand Diels-Alder (iEDDA) reaction with trans-cyclooctene (TCO) compounds, facilitating targeted drug delivery. Additionally, the maleimide functionality exhibits stability in aqueous conditions, making it suitable for various bioconjugation studies and enhancing drug solubility and circulation time.
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