Fig. 1 · Structure
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Mefloquine
Antimalarial Agent
Mefloquine is a potent quinoline antimalarial agent primarily targeting malaria parasites. This compound functions as an effective anti-SARS-CoV-2 entry inhibitor and acts as a K+ channel (KvQT1/minK) antagonist with an IC50 of approximately 1 μM. Mefloquine is suitable for research applications in malaria treatment, systemic lupus erythematosus, and cancer exploration.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 53230-10-7 |
| Applications | Antimalarial Agent |
| Formula | C17H16F6N2O |
| Molecular Weight | 378.31 |
| Synonyms | Mefloquin |
| SMILES | O[C@H]([C@]1([H])NCCCC1)C2=CC(C(F)(F)F)=NC3=C(C(F)(F)F)C=CC=C32 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.