MEK162 (ARRY-438162, Binimetinib)
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | MEK162 (ARRY-438162) is a potent, selective, ATP uncompetitive inhibitor of MEK1/2. | ||
---|---|---|---|
Targets |
|
Catalog Num | A11493 |
---|---|
Formula | C17H15BrF2N4O3 |
Molecular Weight | 440 |
CAS Number | 606143-89-9 |
SMILES | CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)F)C(=O)NOCCO |
Synonyms | ARRY-162, MEK-162, MEK 162 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | Warmed: 86 mg/mL (194.91 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 1% CMC+0.5% Tween-80 | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.73 mL | 113.64 mL | 227.27 mL |
0.5 mM | 4.55 mL | 22.73 mL | 45.45 mL |
1 mM | 2.27 mL | 11.36 mL | 22.73 mL |
5 mM | 0.45 mL | 2.27 mL | 4.55 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2