Fig. 1 · Structure
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Melflufen hydrochloride
Alkylating Agent
Melflufen hydrochloride, an alkylating agent, is a dipeptide prodrug of Melphalan that exhibits significant antitumor activity against multiple myeloma (MM) cells. It functions by inducing irreversible DNA damage, leading to cytotoxic effects in MM cells while also inhibiting angiogenesis. Melflufen hydrochloride serves as a valuable tool for research into cancer therapeutics and the mechanisms of tumor resistance.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 380449-54-7 |
| Applications | Alkylating Agent |
| Formula | C24H31Cl3FN3O3 |
| Molecular Weight | 534.88 |
| Synonyms | Melphalan flufenamide hydrochloride |
| SMILES | O=C(OCC)[C@H](CC1=CC=C(F)C=C1)NC([C@H](CC2=CC=C(N(CCCl)CCCl)C=C2)N)=O.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.