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Melineurine

Acetylcholinesterase Inhibitor, Butyrylcholinesterase Inhibitor

Melineurine is a reversible mixed-type inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting IC50 values of 95.3 μM for AChE and 28.0 μM for BChE. This compound is instrumental in the study of neurodegenerative disorders, particularly Alzheimer's disease, due to its effects on cholinergic signaling. Melineurine serves as a valuable tool for investigating the role of cholinesterase inhibition in cognitive function and related therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	85802-28-4
Applications	Acetylcholinesterase Inhibitor, Butyrylcholinesterase Inhibitor
Formula	C₁₇H₁₇NO₃
Molecular Weight	283.32
SMILES	COC1=C2C=COC2=NC3=C1C=CC(OC/C=C(C)/C)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.