Meloxicam-d3-1 is a deuterium-labeled derivative of Meloxicam, a non-steroidal anti-inflammatory drug that primarily targets cyclooxygenase (COX) enzymes. Its inhibitory activity is characterized by IC50 values of 0.49 µM for COX-2 and 36.6 µM for COX-1, emphasizing its selectivity for COX-2. This stable isotope is valuable for pharmacokinetic studies and metabolic research, offering insights into drug metabolism and distribution pathways.
Meloxicam-d3-1 is a deuterium-labeled derivative of Meloxicam, a non-steroidal anti-inflammatory drug that primarily targets cyclooxygenase (COX) enzymes. Its inhibitory activity is characterized by IC50 values of 0.49 µM for COX-2 and 36.6 µM for COX-1, emphasizing its selectivity for COX-2. This stable isotope is valuable for pharmacokinetic studies and metabolic research, offering insights into drug metabolism and distribution pathways.
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