Documents & Downloads

Memagal

AchE Inhibitor/NMDAR Antagonist

Memagal is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 1.16 nM and acts as an N-methyl-D-aspartate receptor (NMDAR) antagonist with a Ki of 4.6 μM. This compound effectively inhibits neurotoxicity triggered by NMDA, demonstrating an IC50 value of 0.28 nM. Memagal serves as a valuable tool for research focused on Alzheimer's disease, providing insights into mechanisms and potential therapeutic approaches.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1402938-19-5
Applications	AchE Inhibitor/NMDAR Antagonist
Formula	C₃₄H₅₀N₂O₃
Molecular Weight	534.77
SMILES	COC1=C2C([C@](CC3)(C=C[C@@H]4O)[C@@](C4)([H])O2)=C(C=C1)CN3CCCCCCN[C@](C[C@@]5(C6)C)(C[C@@H]6C7)C[C@@]7(C5)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.