Fig. 1 · Structure
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Mepazine hydrochloride
Apoptosis Inducer
Mepazine hydrochloride is a potent apoptosis inducer that selectively inhibits MALT1 protease, exhibiting IC50 values of 0.83 μM for GSTMALT1 full length and 0.42 μM for GSTMALT1 325-760. This compound effectively enhances apoptosis in ABC-DLBCL cells, making it a valuable tool for research into apoptotic mechanisms and therapeutic strategies in cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inducer |
| CAS Number | 2975-36-2 |
| Applications | Apoptosis Inducer |
| Formula | C19H23ClN2S |
| Molecular Weight | 346.92 |
| Synonyms | Pecazine hydrochloride |
| SMILES | CN1CC(CN2C3=C(C=CC=C3)SC4=CC=CC=C24)CCC1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.