Fig. 1 · Structure
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MePhe7-Neurokinin B
NK3R Agonist
[MePhe7]-Neurokinin B is a potent agonist of the neurokinin-3 receptor (NK3R) with an IC50 value of 3 nM. This compound plays a pivotal role in the modulation of pulsatile gonadotropin-releasing hormone (GnRH) secretion through NK3R activation. It is particularly valuable in research focused on reproductive physiology and neuroendocrine signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 110880-53-0 |
| Applications | NK3R Agonist |
| Formula | C60H81N13O14S2 |
| Molecular Weight | 1272.49 |
| SMILES | CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCSC)NC(=O)[C@@H](N)CC(O)=O)C(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.