Fig. 1 · Structure

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MePhe8,Sar9 Substance P

Analog of Substance P

[MePhe8,Sar9] Substance P is an analog of the neuropeptide Substance P, functioning as a neurotransmitter and neuromodulator in the central nervous system (CNS). This compound exhibits biological activity relevant to pain modulation and neuroinflammation. It is utilized in research applications focused on the roles of neuropeptides in various physiological and pathological processes, including nociception and stress responses.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 77128-76-8
Applications Analog of Substance P
Formula C65H102N18O13S
Molecular Weight 1375.68
Synonyms [MePhe8-MeGly9] Substance P
SMILES
CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CN(C)C(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCNC(N)=N)C(N)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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