MeS-IMPY is a selective imaging ligand for β-amyloid plaques, demonstrating high binding affinity to β-amyloid extracted from human brains affected by Alzheimer's disease (AD) with Ki values of 7.93 nM and 8.95 nM for isolated plaques and brain homogenates, respectively. This compound shows promise as a radioligand for positron emission tomography (PET) imaging of β-amyloid plaques, facilitating the evaluation of AD pathology in research applications.
MeS-IMPY is a selective imaging ligand for β-amyloid plaques, demonstrating high binding affinity to β-amyloid extracted from human brains affected by Alzheimer's disease (AD) with Ki values of 7.93 nM and 8.95 nM for isolated plaques and brain homogenates, respectively. This compound shows promise as a radioligand for positron emission tomography (PET) imaging of β-amyloid plaques, facilitating the evaluation of AD pathology in research applications.
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