Mesoridazine-d3 is a deuterium-labeled derivative of Mesoridazine, a phenothiazine antipsychotic that primarily targets human ether-a-go-go related gene (hERG) channels. This compound functions as a rapid open-channel blocker of hERG currents, exhibiting an IC50 value of 550 nM in human embryonic kidney 293 cells. Mesoridazine-d3 is useful in pharmacological studies related to schizophrenia and other psychiatric disorders, facilitating research into the mechanisms underlying these conditions.
Mesoridazine-d3 is a deuterium-labeled derivative of Mesoridazine, a phenothiazine antipsychotic that primarily targets human ether-a-go-go related gene (hERG) channels. This compound functions as a rapid open-channel blocker of hERG currents, exhibiting an IC50 value of 550 nM in human embryonic kidney 293 cells. Mesoridazine-d3 is useful in pharmacological studies related to schizophrenia and other psychiatric disorders, facilitating research into the mechanisms underlying these conditions.
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