Fig. 1 · Structure

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Metallo-β-lactamase-IN-15

MBL Inhibitor

Metallo-β-lactamase-IN-15 is a potent inhibitor of metallo-β-lactamases (MBLs), targeting enzymes such as NDM-1, IMP-1, and VIM-2 with IC50 values of 0.29 μM, 0.088 μM, and 0.063 μM, respectively. This compound is valuable for research into antibiotic resistance mechanisms and the development of novel therapeutic strategies. It may be utilized in studies aimed at understanding the functional role of MBLs in bacterial pathogens.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1804934-57-3
Applications MBL Inhibitor
Formula C10H11NS3
Molecular Weight 241.40
SMILES
SC[C@H]1SC[C@]2([H])SC3=CC=CC=C3N21

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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