Fig. 1 · Structure

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Methyl 3-bromopropanoate

PROTAC Linker

Methyl 3-bromopropanoate is a key PROTAC linker that facilitates the design and synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound plays a critical role in enabling targeted protein degradation, supporting research into therapeutic strategies for various diseases by modulating protein levels in cellular contexts. Its application in linking warheads to ligands makes it an essential reagent for developing innovative biopharmaceuticals.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 3395-91-3
Applications PROTAC Linker
Formula C4H7BrO2
Molecular Weight 167.00
SMILES
O=C(OC)CCBr

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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