Fig. 1 · Structure
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Methyl 5-bromo-4-oxopentanoate
PROTAC Linker
Methyl 5-bromo-4-oxopentanoate is a chemical linker designed for use in the development of Proteolysis Targeting Chimeras (PROTACs). This compound plays a crucial role in the synthesis of PROTACs, facilitating the targeted degradation of proteins by recruiting an E3 ligase. It is essential for researchers investigating targeted protein degradation and exploring therapeutic avenues in cancer and other diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 53856-93-2 |
| Applications | PROTAC Linker |
| Formula | C6H9BrO3 |
| Molecular Weight | 209.04 |
| SMILES | O=C(OC)CCC(=O)CBr |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.