Methyl azetidine-3-carboxylate hydrochloride

Catalog No.: A42588
ADC Linker
Methyl azetidine-3-carboxylate hydrochloride is a non-cleavable linker for antibody-drug conjugates (ADCs) that facilitates the stable attachment of cytotoxic agents to antibodies. This compound also serves as an alkyl chain-based linker in the development of PROTACs (proteolysis-targeting chimeras), enabling targeted protein degradation. Its robust chemical properties make it essential for advancing research in targeted therapeutics and drug delivery systems.
Grouped product items
Size Price Stock Qty
1g
$25.00
In stock
5g
$55.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMethyl azetidine-3-carboxylate hydrochloride is a non-cleavable linker for antibody-drug conjugates (ADCs) that facilitates the stable attachment of cytotoxic agents to antibodies. This compound also serves as an alkyl chain-based linker in the development of PROTACs (proteolysis-targeting chimeras), enabling targeted protein degradation. Its robust chemical properties make it essential for advancing research in targeted therapeutics and drug delivery systems.
Product Information
Catalog NumA42588
FormulaC5H10ClNO2
Molecular Weight151.59
CAS Number100202-39-9
SMILESO=C(C1CNC1)OC.[H]Cl
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

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