Methyl betulonate, a triterpenoid derivative of betulonic acid, exhibits potent inhibitory effects on cell growth across various tumor cell lines, including those resistant to conventional treatments. This compound demonstrates an IC50 greater than 50.0 μM in inhibiting the proliferation of eight tumor and two normal fibroblast cell lines. Methyl betulonate is valuable in cancer research, particularly for studies focused on understanding the mechanisms of tumor cell resistance and evaluating potential anti-cancer therapies.
Methyl betulonate, a triterpenoid derivative of betulonic acid, exhibits potent inhibitory effects on cell growth across various tumor cell lines, including those resistant to conventional treatments. This compound demonstrates an IC50 greater than 50.0 μM in inhibiting the proliferation of eight tumor and two normal fibroblast cell lines. Methyl betulonate is valuable in cancer research, particularly for studies focused on understanding the mechanisms of tumor cell resistance and evaluating potential anti-cancer therapies.
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