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Methyl ganoderate A acetonide

AChE Inhibitor

Methyl ganoderate A acetonide is a lanostane triterpene that functions as a potent acetylcholinesterase (AChE) inhibitor, exhibiting an IC50 value of 18.35 μM. This natural compound, extracted from the fruiting bodies of Ganoderma lucidum, is utilized in research efforts focused on Alzheimer's disease (AD). Its inhibition of AChE makes it a valuable tool for investigating therapeutic strategies for cognitive decline associated with neurodegenerative disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1346453-53-9
Applications	AChE Inhibitor
Formula	C₃₄H₅₀O₇
Molecular Weight	570.76
SMILES	C[C@@]12C3=C4[C@@]5([C@@](C(C)(C(CC5)=O)C)([H])C[C@]3([H])OC(C)(O[C@@]1([H])C[C@]([C@]2(CC4=O)C)([H])[C@H](C)CC(C[C@@H](C)C(OC)=O)=O)C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.