Methyl kakuol

Catalog No.: A68791
TRPA1 Agonist
Methyl kakuol is a selective agonist of the transient receptor potential ankyrin 1 (TRPA1) channel, exhibiting an effective concentration (EC50) of 0.27 µM. This compound facilitates the activation of TRPA1, making it a valuable tool for research into sensory pathways and pain mechanisms. Its ability to modulate TRPA1 activity can aid in the exploration of neurophysiological responses and the development of therapeutic strategies targeting pain and inflammation.
Grouped product items
Size Price Stock Qty
1mg
$55.00
In stock
2mg
$80.00
In stock
5mg
$135.00
In stock
10mg
$225.00
In stock
25mg
$365.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMethyl kakuol is a selective agonist of the transient receptor potential ankyrin 1 (TRPA1) channel, exhibiting an effective concentration (EC50) of 0.27 µM. This compound facilitates the activation of TRPA1, making it a valuable tool for research into sensory pathways and pain mechanisms. Its ability to modulate TRPA1 activity can aid in the exploration of neurophysiological responses and the development of therapeutic strategies targeting pain and inflammation.
Product Information
Catalog NumA68791
FormulaC11H12O4
Molecular Weight208.21
CAS Number70342-29-9
SMILESO=C(C(C=C(OCO1)C1=C2)=C2OC)CC
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