Fig. 1 · Structure
Documents & Downloads
Methyl-PEG2-alcohol
PROTAC Linker
Methyl-PEG2-alcohol is a polyethylene glycol (PEG) based linker specifically designed for use in the synthesis of PROTAC (proteolysis-targeting chimeras). This compound facilitates the conjugation of a ligand to an E3 ubiquitin ligase, enabling targeted protein degradation. Its application in PROTAC development allows researchers to study protein function and degradation pathways, contributing to advancements in therapeutic discovery and drug development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 111-77-3 |
| Applications | PROTAC Linker |
| Formula | C5H12O3 |
| Molecular Weight | 120.15 |
| SMILES | COCCOCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.