Fig. 1 · Structure
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Methyl pseudolarate B
PTP1B Inhibitor
Methyl pseudolarate B is a natural diterpenoid that serves as an inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 10.9 μM. This compound is significant in the study of insulin signaling and metabolic disorders, making it a valuable tool for research applications focused on diabetes and obesity. Its inhibition of PTP1B can help elucidate mechanisms underlying cellular signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 82508-34-7 |
| Applications | PTP1B Inhibitor |
| Formula | C24H30O8 |
| Molecular Weight | 446.49 |
| SMILES | CC(O[C@]12[C@]3(CC=C(C(OC)=O)CC2)CC[C@@]1([H])[C@](/C=C/C=C(C)/C(OC)=O)(C)OC3=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.