Fig. 1 · Structure

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Methylamino-PEG5-azide

PROTAC Linker

Methylamino-PEG5-azide is a PEG-based linker designed for use in PROTAC synthesis, targeting protein degradation pathways. Featuring an azide moiety, it participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing partners, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalities. This versatile reagent is essential for the development of novel PROTAC compounds, facilitating targeted protein degradation research and applications in drug discovery.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2055046-24-5
Applications PROTAC Linker
Formula C13H28N4O5
Molecular Weight 320.39
SMILES
CNCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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