METTL1-WDR4-IN-2 is a selective inhibitor of the METTL1-WDR4 methyltransferase complex, exhibiting an IC50 value of 41 μM. This compound demonstrates significant selectivity, with IC50 values of 958 μM against METTL3-14 and 208 μM against METTL16. METTL1-WDR4-IN-2 is valuable for investigating the role of RNA methylation in cancer and other biological processes related to epitranscriptomics.
METTL1-WDR4-IN-2 is a selective inhibitor of the METTL1-WDR4 methyltransferase complex, exhibiting an IC50 value of 41 μM. This compound demonstrates significant selectivity, with IC50 values of 958 μM against METTL3-14 and 208 μM against METTL16. METTL1-WDR4-IN-2 is valuable for investigating the role of RNA methylation in cancer and other biological processes related to epitranscriptomics.
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