Fig. 1 · Structure
Documents & Downloads
MF-766
EP4 Antagonist
MF-766 is a potent and selective EP4 antagonist, exhibiting a Ki value of 0.23 nM. It functions as a full antagonist in functional assays, displaying an IC50 of 1.4 nM, which slightly increases to 1.8 nM in the presence of 10% human serum. This reagent is valuable for research related to cancer and inflammatory diseases, facilitating the exploration of EP4 pathways in therapeutic contexts.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1050656-06-8 |
| Applications | EP4 Antagonist |
| Formula | C27H21F3N2O3 |
| Molecular Weight | 478.46 |
| SMILES | O=C(O)C1=CC=C(C2(NC(C3=CC=CC4=C3N(CC5=CC=C(C(F)(F)F)C=C5)C=C4)=O)CC2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.