MFZ 10-7 is a highly potent and selective negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5), exhibiting a Ki of 0.67 nM for rat mGluR5. This compound serves as an essential tool for investigating the pharmacological modulation of mGluR5 activity, particularly in studies of psychiatric and neurodegenerative disorders. Additionally, MFZ 10-7 contains an alkyne group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc), making it suitable for applications in click chemistry.
MFZ 10-7 is a highly potent and selective negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5), exhibiting a Ki of 0.67 nM for rat mGluR5. This compound serves as an essential tool for investigating the pharmacological modulation of mGluR5 activity, particularly in studies of psychiatric and neurodegenerative disorders. Additionally, MFZ 10-7 contains an alkyne group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc), making it suitable for applications in click chemistry.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
