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MGL-IN-2

MGL Inhibitor

MGL-IN-2 is a potent inhibitor of monoacylglycerol lipase (MGL), exhibiting IC50 values of 0.006 μM for mutant MGL and 0.0121 μM for wild-type MGL. This compound effectively modulates MGL activity, making it a valuable tool for investigating metabolic disorders and related pathways. Research applications include the study of endocannabinoid signaling and its implications in metabolic disease research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1252773-92-4
Applications	MGL Inhibitor
Formula	C₂₁H₁₈ClF₃N₄O₂S₂
Molecular Weight	514.97
SMILES	O=C(C1=CSC=N1)N2CCN(C3CN(C(C4=C(Cl)C5=CC=C(C(F)(F)F)C=C5S4)=O)C3)CC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.