Fig. 1 · Structure
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Milnacipran-d10 hydrochloride
Cat. No.
A56885
CAS
1217774-40-7
Stable Isotope
Milnacipran-d10 hydrochloride is a deuterium-labeled form of the serotonin and norepinephrine reuptake inhibitor, Milnacipran hydrochloride. It effectively inhibits monoamine transporters, targeting the norepinephrine and serotonin transporters with reported Ki values of 31 nM and 8.5 nM, respectively. This compound exhibits antidepressant, anxiolytic, and analgesic properties, and has demonstrated efficacy in reducing biting behavior in murine models. Milnacipran-d10 hydrochloride is valuable for research applications focused on major depressive disorder, anxiety disorders, and neuropathic pain syndromes, such as fibromyalgia.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1217774-40-7 |
| Applications | Stable Isotope |
| Formula | C15H13D10ClN2O |
| Molecular Weight | 292.87 |
| SMILES | C(N(C(C([2H])([2H])[2H])([2H])[2H])C(C([2H])([2H])[2H])([2H])[2H])(=O)[C@]1([C@@H](CN)C1)C2=CC=CC=C2.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.