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Biological Activity
MIRA-1 restores wild-type conformation, function and DNA binding activity to mutant p53. Induces p53 transcriptional transactivation of p21, MDM2 and PUMA.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 54.6 mL | 272.99 mL | 545.97 mL |
| 0.5 mM | 10.92 mL | 54.6 mL | 109.19 mL |
| 1 mM | 5.46 mL | 27.3 mL | 54.6 mL |
| 5 mM | 1.09 mL | 5.46 mL | 10.92 mL |
*The above data is based on the productmolecular weight 183.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15348 |
|---|---|
| Actions | Inducer |
| CAS No. | 72835-26-8 |
| Formula | C8H9NO4 |
| M. Wt | 183.16 |
| Purity | >98% |
| SMILES | CCC(=O)OCN1C(=O)C=CC1=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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